It is also important for us to know if ‘nothing at all changed in any way’.  This means that the chemical mixture did NOT trigger the person’s healing system, and we will need to alter that mixture going forward.  This does NOT mean that Prolotherapy per se will not ‘work’, just that we either need a new chemical mix to adequately stimulate their system, or even on occasion that their healing system is functioning so poorly that we need to diagnose and remedy a systemic problem before we can obtain the desired results.